VPCIR ™ REEAD

VPCIR ™ REEAD (Rolling Circle Enhance Enzyme Activity Detection) product line is focused on measurement of topoisomerase 1 (TOP1) activity.

They are assay kits for measurement of overall TOP1 activity (VPCIR ™ REEAD TOP1 activity) and will also include an assay capable of measuring the cleavage and ligation activity of TOP1 separately (VPCIR ™ REEAD C|L TOP1 activity).

These products may be used with various inputs recombinant type B TOP1 (e.g., human nuclear, human mitochondrial, monkeypox, malaria).

VPCIR ™ REEAD are used for:

Drug screening for TOP1 inhibitors in chemotherapy
Drug screening for TOP1 inhibitors for protozoal pathogens
Research in certain cancers
Research in certain chronic and infectious diseases
Tests for malaria (Plasmodium) and other protozoa, and for monkeypox

Value Proposition

Current gel-based method is technically sensible. The VPCIR ™ REEAD format provides more reproducible and dependable results.

Extremely rapid – 25 times higher thru-put than current alternative (gel-based) method

Little requirement of specialized training nor expensive laboratory equipment or reader.

User friendly, small laboratory footprint.

In pathogen testing the kits are ultra-rapid (point-of-care) and user-friendly – can be used in field station situations.